Figure 3
From: ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs
UCP1-expressing bmMSC-derived adipocytes show increased mitochondrial and uncoupled respiration upon forskolin stimulation.
Oxidative respiratory capacity (OCR) was measured in bmMSC-derived adipocytes ± MMC to assess the extent of increase in mitochondrial and uncoupled respiration in response to a forskolin (10 μM) stimulus. Respiratory profiles of (a) iw vs. iw MMC, (b) ib vs. ib MMC and (c) iw vs. ib MMC. Data is expressed as mean ± SEM. n.s. =not significant; *p < 0.05; **p < 0.01; ***p < 0.001. N = 5.
