Table 3 Endocrinal and metabolic characteristics comparison of rs174570 T/C using additive model in PCOS cases.
From: FADS1-FADS2 gene cluster confers risk to polycystic ovary syndrome
TT(n = 132) | TC(n = 745) | CC(n = 968) | BETA | P | BETA-adj | P-adj | |
|---|---|---|---|---|---|---|---|
FSH (IU/L) | 6.35 ± 1.88 | 6.15 ± 1.89 | 6.26 ± 1.56 | 0.028 | 0.681 | 0.035 | 0.611 |
LH (IU/L) | 10.87 ± 5.92 | 10.43 ± 6.46 | 10.41 ± 5.69 | −0.129 | 0.589 | −0.125 | 0.592 |
T (ng/dl) | 43.74 ± 19.23 | 42.38 ± 17.81 | 45.37 ± 28.21 | 1.843 | 0.053 | 1.629 | 0.085 |
F-GLU (mmol/l) | 5.57 ± 1.26 | 5.48 ± 0.88 | 5.48 ± 0.91 | −0.023 | 0.535 | −0.021 | 0.554 |
F-INS (mIU/L) | 13.78 ± 7.90 | 13.72 ± 8.70 | 13.96 ± 9.29 | 0.163 | 0.649 | 0.054 | 0.845 |
HOMA-IR | 3.58 ± 2.85 | 3.45 ± 2.62 | 3.50 ± 2.74 | 0.003 | 0.977 | 0.048 | 0.590 |
TC (mmol/l) | 4.46 ± 0.85 | 4.51 ± 0.87 | 4.52 ± 0.82 | 0.019 | 0.577 | 0.020 | 0.524 |
TG (mmol/l) | 1.35 ± 0.70 | 1.42 ± 1.37 | 1.38 ± 1.25 | −0.014 | 0.789 | −0.019 | 0.704 |
HDL-C (mmol/l) | 1.31 ± 0.29 | 1.33 ± 0.32 | 1.31 ± 0.30 | −0.011 | 0.354 | −0.008 | 0.501 |
LDL-C (mmol/l) | 3.18 ± 0.97 | 3.11 ± 0.90 | 3.12 ± 0.90 | −0.013 | 0.718 | −0.018 | 0.591 |
