Figure 1: p-mTOR, p-p70S6K, p-4E-BP1 and p-AKT expression in HCL (X600).

(A) Cytoplasmic p-mTOR immunoreactivity in hairy cells. Note the negative precursor erythroid cells marked with black stars (*). (B) Nuclear and cytoplasmic p-p70S6K immunoreactivity in hairy cells. (C) Nuclear and cytoplasmic p-4E-BP1 immunoreactivity in hairy cells. (D) Punctate cytoplasmic p-AKT immunoreactivity in hairy cells. Note the presence of scattered positive nuclei (*) in another case in inset.