Figure 1: Estrous cycles were monitored for 12 days in CTL (placebo) and DHT-treated wild type and CMKLR1 null mice (nā€‰=ā€‰10). | Scientific Reports

Figure 1: Estrous cycles were monitored for 12 days in CTL (placebo) and DHT-treated wild type and CMKLR1 null mice (nā€‰=ā€‰10).

From: CMKLR1 deficiency maintains ovarian steroid production in mice treated chronically with dihydrotestosterone

Figure 1

(A) Both control wild type and CMKLR1 null mice underwent 2ā€“3 regular estrous cycles. Estrous cycles were absent in DHT-treated wild type mice; however, DHT-treated CMKLR1 null mice underwent 1ā€“2 estrous cycles. (B) Quantification showed that CMKLR1 deficiency prevented the acyclicity induced by DHT. E, estrous cycle; P/M, proestrous cycle and metaestrous cycle; D, diestrous cycle. WT control, placebo-treated wild type mice; WT-DHT, DHT-treated wild type mice; cmklr1āˆ’/āˆ’ control, placebo-treated CMKLR1 null mice; cmklr1āˆ’/āˆ’ DHT, DHT-treated CMKLR1 null mice. Data were analyzed using an unpaired Studentā€™s t test. (a) p, DHT-treated vs. control wild type mice; (b) p, DHT-treated vs. control CMKLR1-null mice; (d) p, DHT-treated CMKLR1 null mice vs. DHT-treated wild type mice.

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