Figure 9: Antral follicles were collected after PMSG treatment for 48 h and further treated under different conditions for 6 h.

StAR, p450scc, and 3βHSD mRNA expression and estradiol and progesterone production in antral follicles of wild type mice or CMKLR1 null mice were measured. Data were analyzed by an unpaired Student’s t test. #p, compared with non-hCG treatment group (#p < 0.05; ##p < 0.01; ##p < 0.001); *p compared with hCG-treated follicles (*p < 0.05; **p < 0.01; ***p < 0.001); @p, compared with DAN-treated follicles in the presence of hCG (@p < 0.05).