Figure 6 | Scientific Reports

Figure 6

From: Discovery of Radioiodinated Monomeric Anthraquinones as a Novel Class of Necrosis Avid Agents for Early Imaging of Necrotic Myocardium

Figure 6

Biodistribution and postmortem analyze of MI in rats.

(a) Biodistribution of 131I-rhein or 131I-Hyp at 6 h after administration (n = 5 per tracer). Data are expressed as average percentage of injected dose per gram (%ID/g) ± SD: Viable.m = viable myocardium, Necrotic.m = necrotic myocardium; (b–e) Postmortem analyze of necrotic and viable myocardium from model rats of 131I-rhein: (b) TTC staining image of 2 mm thick slice; (c) autoradiogram from 50 μm frozen section; (d) H&E staining image of 10 μm frozen section; (e) H&E-stained microphotograph proved the presence of necrosis: N = necrotic area, V = viable area.

Back to article page