Figure 3: DP diet prevented gamma radiation-induced cancellous bone loss.
From: Dried plum diet protects from bone loss caused by ionizing radiation
Mice were fed control diet (CD3) or DP diet, then irradiated with 137Cs (2 Gy). After irradiation (11d), mice were euthanized and tibiae collected. Bones were analyzed by microCT for percent bone volume (BV/TV, Panel A), trabecular number (Tb.N, Panel B), trabecular separation (Tb.Sp, Panel C) and trabecular thickness (Tb.Th, Panel D). Representative images of the cancellous bone microarchitecure in 3D reconstructions using the microCT are shown in (panel E). Data shown are mean + S.D. (n = 8/group) and analyzed by 2-factor ANOVA. *indicates p < 0.05 compared to CD3/sham-irradiated controls by Dunnett’s post hoc test.
