Figure 6 | Scientific Reports

Figure 6

From: Three-Dimensional Characterization of Mechanical Interactions between Endothelial Cells and Extracellular Matrix during Angiogenic Sprouting

Figure 6

Sprout elongation with both lamellipodial protrusion and retraction over a period of nearly 2 hours.

The tip cell heading (marked by arrows) varied with the different evolving processes of tip cell lamellipodium branches B1 and B2. The sprout changed its heading from the long-axis direction of B1 that was undergoing retraction to that of B2 continually protruding.

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