Figure 7

The 2-hour dynamics of interaction with the ECM of the two tip-cell lamellipodium branches, B1 and B2, which exhibited distinct morphological changes (shown in Fig. 6) during this period.
Panels (A,C) reveal the involvement of the four interaction behavior types at each time point for B1 and B2, respectively. It is important to note that only the deformation appearing between two adjacent time points is reflected in the result for the latter time point, meaning that deformation did not accumulate over time. (B) shows a comparison in the pull scale between B1 and B2. The significance of the difference was evaluated with an independent samples t-test in IBM SPSS Statistics 22 (P < 0.05). (D) shows a comparison of the scales of both protrusion and retraction for B1. (E) lists the computed Pearson correlation coefficients for these six pairs of interaction behavior types.