Table 3 Risk factors associated with anal infection for 37 HPV subtypes.

From: Anal HPV/HIV co-infection among Men Who Have Sex with Men: a cross-sectional survey from three cities in China

Variables	Prevalence n/N^* (%)	OR (95% CI)	P-value	Adjusted OR (95% CI)	P-value
Site			0.00
Chengdu	193/281 (68.69)	Ref.	Ref.	Ref.	Ref.
Xi’an	135/256 (52.73)	0.79 (0.56–1.10)	0.17	0.73 (0.49–1.07)	0.11
Taiyuan	208/285 (72.98)	2.06 (1.48–2.86)	0.00	2.13 (1.48–3.05)	0.00
Age			0.012
≤29 years	259/392 (66.07)	Ref.	Ref.	Ref.	Ref.
30–39 years	170/261 (65.13)	0.91 (0.64–1.29)	0.59	0.79 (0.50–1.24)	0.30
≥40 years	108/169 (63.91)	1.00 (0.69–1.47)	0.82	0.99 (0.65–1.52)	0.97
Education			0.002
≤9 years	71/105 (67.62)	Ref.	Ref.	Ref.	Ref.
10–12 years	115/170 (67.65)	0.89 (0.55–1.44)	0.63	0.82 (0.48–1.38)	0.45
>12 years	351/547 (64.17)	1.07 (0.77–1.50)	0.68	1.29 (0.87–1.91)	0.21
Marriage status			0.20
Unmarried	361/551 (65.52)	Ref.	Ref.
Married	134/205 (65.36)	0.89 (0.55–1.46)	0.65
Divorced or widowed	42/66 (63.64)	0.84 (0.49–1.44)	0.52
Self-reported sexual orientation			0.31
Homosexual	385/574 (67.07)	Ref.	Ref.
Heterosexual	5/9 (55.56)	0.90 (0.45–1.81)	0.76
Bisexual	127/206 (61.65)	1.14 (0.26–5.20)	0.86
Not sure	20/33 (60.61)	1.04 (0.50–2.16)	0.93
Ever had sex with women			0.00
Yes	255/399 (63.91)	Ref.	Ref.	Ref.	Ref.
No	282/513 (54.97)	1.09 (0.84–1.43)	0.52	1.06 (0.75–1.51)	0.74
Age at the first homosexual act			0.00
<18 years	87/220 (39.55)	Ref.	Ref.	Ref.	Ref.
≥18 years	447602 (74.25)	1.00 (0.74–1.35)	0.99	1.02 (0.71–1.46)	0.93
Ever had Genital wart			0.00
No	60/85 (70.59)	Ref.	Ref.	Ref.	Ref.
Yes	477/737 (64.72)	0.71 (0.45–1.14)	0.12	0.75 (0.45–1.25)	0.27
Ever had other STDs			0.00
No	83/118 (69.70)	Ref.	Ref.	Ref.	Ref.
Yes	453/704 (64.35)	0.84 (0.57–1.24)	0.38	0.85 (0.55–1.30)	0.45
Have current sexual partner			0.00
No	224/345 (64.93)	Ref.	Ref.
Yes	313/477 (65.62)	0.84 (0.57–1.24)	0.67	0.99 (0.72–1.36)	0.94
Frequency of homosexual behaviors in the past 6 months			0.00
<once a week	401/615 (65.20)	Ref.	Ref.	Ref.	Ref.
≥once a week	105/207 (50.72)	1.15 (0.83–1.60)	0.41	1.01 (0.69–1.48)	0.96
Condom use during insertive anal sex in the past 6 months			0.00
Always	359/548 (65.51)	Ref.	Ref.	Ref.	Ref.
Sometimes/Never	146/274 (53.28)	0.97 (0.72–1.31)	0.84	1.21 (0.87–1.70)	0.26
Number of homosexual partners in the past 6 months			0.00
≤1	151/240 (62.92)	Ref.	Ref.	Ref.	Ref.
2–5	298/464 (64.22)	1.76 (1.12–2.77)	0.15	1.80 (0.99–3.24)	0.05
≥6	86/117 (73.50)	1.56 (1.02–2.37)	0.04	1.65 (1.00–2.73)	0.05
Number of homosexual partners ever had			0.00
1–5	126/235 (53.62)	Ref.	Ref.	Ref.	Ref.
6–10	153/259 (59.07)	1.51 (0.98–2.35)	0.06	1.09 (0.62–1.92)	0.75
11–30	174/263 (66.16)	1.21 (0.79–1.87)	0.38	0.88 (0.52–1.48)	0.63
>30	84/132 (63.64)	0.90 (0.58–1.39)	0.02	0.71 (0.43–1.15)	0.16
Ever had multiple partner sex in the past year			0.00
No	62/87 (71.26)	Ref.	Ref.	Ref.	Ref.
Yes	473/735 (64.35)	0.61 (0.38–0.99)	0.04	0.50 (0.29–0.87)	0.01
Ever had paid sex with man in the past year			0.00
No	19/36 (52.78)	Ref.	Ref.	Ref.	Ref.
Yes	515/781 (65.94)	1.83 (0.97–3.43)	0.06	2.34 (1.16–4.74)	0.02
Ever found sexual partners in gay venues			0.00
No	363/574 (63.24)	Ref.	Ref.	Ref.	Ref.
Yes	173/248 (69.76)	1.30 (0.96–1.75)	0.99	0.88 (0.36–2.20)	0.79

Abbreviation: CI, confidence intervals; OR, odds ratio; STD, sexual transmitted disease.
^*Sum may not always add up to total because of missing data.

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Table 3 Risk factors associated with anal infection for 37 HPV subtypes.

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