Table 5 The association of anal HPV infection with HIV-1 seropositivity by oncogenic type and multiplicity of HPV types.

Anal infection of 37 HPV types	Prevalence of HIV-1 seropositivity n/N (%)	OR (95% CI)	Adjusted OR^* (95% CI)
By oncogenic type
Negative for any type	18/285(6.32)	Ref.	Ref.
Only Positive for low-risk type	13/118(11.02)	2.18 (1.30–3.66)	2.43 (1.42–4.16)
Only Positive for high-risk type	40/291(13.75)	2.81 (1.39–5.65)	2.91 (1.40–6.02)
Positive for both	30/124(24.19)	4.86 (2.64–8.96)	5.69 (3.00–10.81)
By multiplicity of HPV types
0	18/285(6.32)	Ref.	Ref.
1	36/314(11.46)	2.38 (1.01–5.59)	2.64 (1.09–6.38)
2	18/120(15.00)	3.99 (1.84–8.63)	4.18 (1.88–9.31)
3	13/57(22.81)	5.43 (2.75–10.75)	5.59 (2.91–11.92)
≥4	19/46(41.30)	9.85 (4.66–20.84)	11.46 (5.25–25.00)
p for trend		<0.01	<0.01

Abbreviation: CI, confidence intervals; OR, odds ratio.
^*Adjusted for age, ethnicity, education, age at the first homosexual act, frequency of homosexual behaviors in the past 6 months and ever found sexual partners in gay venues.

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