Table 1 MRI and fluorescence data obtained for each mouse.
Mouse | Fluorescence | Permeability | Water Diffusion Coefficient | Vessel diameter | Blood Volume fraction | ||
---|---|---|---|---|---|---|---|
# | mean (RLU/pixel/50 ms) | AUC | μm2/s | μm | % | ||
Subcutaneous | HUH-7 | 1 | 689 | 98,522 | 998 | 12.41 | 2.17 |
2 | 1,211 | 135,335 | 1,156 | 12.77 | 2.04 | ||
3 | 1,580 | 139,081 | 1,219 | 14.55 | 3.16 | ||
HEK293(β3) | 1 | 4,659 | 420,034 | 827 | 14.48 | 1.28 | |
2 | 4,941 | 381,695 | 1,232 | 14.34 | 1.02 | ||
3 | 4,790 | 269,158 | 879 | 10.54 | 1.25 | ||
IGROV1 | 1 | 9,682 | 795,062 | 1,537 | 14.12 | 2.44 | |
2 | 12,505 | 519,448 | 1,495 | 13.05 | 2.86 | ||
3 | 16,574 | 752,720 | 1,092 | 17.24 | 1.83 | ||
4 | 10,288 | 569,030 | 1,356 | 15.86 | 2.81 | ||
HT29 | 1 | 13,953 | 590,555 | 1,623 | 13.27 | 2.19 | |
2 | 11,062 | 361,986 | 1,762 | 14.47 | 2.22 | ||
3 | 17,997 | 316,137 | 1,413 | 14.11 | 2.09 | ||
4 | 6,252 | 350,655 | 1,216 | 12.69 | 1.66 | ||
5 | 10,573 | 609,850 | 1,345 | 16.70 | 2.73 | ||
TS/a-pc | 1 | 23,076 | 820,437 | 1,073 | 14.06 | 3.14 | |
2 | 13,094 | 622,315 | 948 | 12.16 | 2.42 | ||
3 | 9,761 | 302,853 | 965 | 11.94 | 2.41 | ||
U87MG | 1 | 12,935 | 365,001 | 1,150 | 11.47 | 1.79 | |
2 | 14,224 | 779,970 | 1,209 | 13.55 | 3.21 | ||
3 | 8,943 | 521,711 | 1,142 | 13.51 | 2.14 | ||
Orthotopic | TS/a-pc | 1 | 8,589 | 677,228 | 882 | 13.43 | 2.34 |
2 | 10,311 | 677,525 | 1,292 | 15.67 | 2.67 | ||
3 | 9,897 | 838,269 | 1,602 | 17.17 | 3.10 | ||
4 | 19,681 | 447,632 | 1,479 | 18.14 | 3.68 | ||
5 | 21,012 | 352,881 | 1,133 | 17.00 | 3.68 | ||
6 | 21,471 | 452,775 | 1,539 | 16.60 | 2.68 | ||
U87MG | 1 | 10,151 | 677,864 | 798 | 13.19 | 6.17 | |
2 | 7,573 | 305,940 | 817 | 12.40 | 6.16 | ||
3 | 8,891 | 414,801 | 783 | 16.60 | 8.40 | ||
4 | 11,986 | 505,689 | 806 | 12.40 | 6.16 | ||
5 | 15,298 | 430,359 | 880 | 13.91 | 7.92 | ||
6 | 12,594 | 552,622 | 906 | 13.11 | 7.89 | ||
7 | 12,197 | 720,627 | 884 | 12.98 | 6.15 | ||
8 | 13,530 | 467,415 | 856 | 10.89 | 5.82 |