Figure 4: Lat-B dose-dependently increased outflow facility. | Scientific Reports

Figure 4: Lat-B dose-dependently increased outflow facility.

From: Dose- and time-dependent effects of actomyosin inhibition on live mouse outflow resistance and aqueous drainage tissues

Figure 4

(A) Lat-B (▲, 10 μM, n = 6; ●, 5 μM, n = 7; □, 2,5 μM, n = 5) or vehicle (♦, n = 5) was delivered to the live mouse anterior chamber and incubated for 1 hour, then 2-level constant pressure perfusion was performed. 5 μM and 10 μM Lat-B increased outflow facility compared with 2.5 μM and vehicle controls (ethanol 0.02%). Outflow facility following 2.5 μM Lat-B and vehicle was similar. Data points: mean outflow facility ± standard error of mean. (B) Statistical analysis of outflow facility based on 2-level constant pressure perfusion following live mouse anterior chamber Lat-B delivery.

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