Figure 6 | Scientific Reports

Figure 6

From: Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery

Figure 6

In vitro release and biodistribution at 24 h.

(A) Release of compound 2 from liposomal system LP-2 in physiological conditions, with 50 mg/mL of BSA, at 37 °C. (B) Concentration of compound 2 determined in plasma, brain, liver and adipose tissue, after the administration of the free drug 2 (black) and the liposomal formulation LP-2 (grey). aThe concentration is expressed as μg/mL for plasma and as μg/g for brain, liver and adipose tissue.

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