Figure 3 | Scientific Reports

Figure 3

From: Dynamic monitoring of cell mechanical properties using profile microindentation

Figure 3

Comparison of apparent stiffness obtained by AFM and profile microindentation.

(a) The difference between the two means is not statistically significant (p = 0.55; two-tailed Student’s t-test). Data are mean ± s.e.m. n = 5 cells for AFM and n = 10 cells for profile microindentation. (b) Probability density for the measure of the apparent stiffness of a given cell normalized by the mean apparent stiffness found for that cell. Black is for AFM and grey for profile microindentation. The same cells as in panel a are used. (c) Top view of AFM measurement of HUVEC rigidity. (Inset) Side view of the spherical probe glued to the tip used in the AFM measurement. (d) Side view of profile microindentation measurement of HUVEC rigidity.

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