Table 1 Main characteristics of the included studies.

From: Prognostic role of microscopically positive margins for primary gastrointestinal stromal tumors: a systematic review and meta-analysis

Study

Year

Sample size

R0 resection

Recurrence in R0 resection

R1 resection

Recurrence in R1 resection

Adjuvant imatinib treatment

Survival analysis

Outcomes

Follow-up (median, range)

Quality score

Cananzi et al.

2014

92

86

31

6

2

Yes

Kaplan–Meier

DFS, OS

41, 2–145 months

7

Jakob et al.

2013

36

24

3

12

4

Yes

Kaplan–Meier

DFS, OS

41, 3–110 months

7

McCarter et al.

2012

817

745

204

72

26

Yes

Kaplan–Meier

DFS

49 months

8

Kim et al.

2012

136

122

5

14

0

No

Kaplan–Meier

DFS

29, 3–106 months

7

Huang et al.

2012

85

82

NR

3

NR

Yes

Kaplan–Meier

DFS, OS

41, 3–100 months

7

Catena et al.

2012

151

132

71

19

6

No

Cox regression

DFS

101, 11–132 months

7

Nikfarjam et al.

2008

40

35

NR

5

NR

Yes

Kaplan–Meier

DFS, OS

24, 1–74 months

7

Gouveia et al.

2008

96

78

7

18

5

No

Cox regression

DFS, OS

42, 1–206 months

7

Rutkowski et al.

2007

328

253

151

75

29

No

Cox regression

DFS

31, 4–292 months

7

Wu et al.

2006

85

81

NR

4

NR

No

Cox regression

DFS, OS

33, 5–202 months

7

Pierie et al.

2001

39

35

13

4

3

No

Cox regression

DFS, OS

38, 1–159 months

7

DeMatteo et al.

2000

80

65

NR

15

NR

No

Kaplan–Meier

OS

24, 1–175 months

7

  1. DFS, disease-free survival; OS, overall survival; NR, not reported.