Table 3 Meta-regression and stratified analysis of pooled hazard ratios of R1 resection for disease-free survival.
Stratified analysis | No. of studies | No. of patients | Pooled HR (95% CI) | Heterogeneity | Meta-regression | |||
|---|---|---|---|---|---|---|---|---|
Fixed | Random | I2 | p-value | Residual I2 | p-value | |||
Overall | 12 | 1905 | 1.567 (1.246–1.969) | 1.596 (1.128–2.258) | 37.5% | 0.091* | ||
Adjuvant imatinib treatment | 34.47% | 0.252 | ||||||
Yes | 5 | 717 | 1.193 (0.784–1.815) | 1.308 (0.583–2.935) | 53.2% | 0.074* | ||
No | 7 | 1188 | 1.758 (1.338–2.310) | 1.785 (1.298–2.456) | 11.3% | 0.343 | ||
Sample size | 40.36% | 0.523 | ||||||
>100 | 5 | 1432 | 1.495 (1.161–1.924) | 1.472 (1.024–2.116) | 39.6% | 0.157 | ||
<100 | 7 | 473 | 1.940 (1.132–3.325) | 1.897 (0.922–3.902) | 41.5% | 0.115 | ||
