Table 4 Meta-regression and stratified analysis of pooled hazard ratios of R1 resection for overall survival.

From: Prognostic role of microscopically positive margins for primary gastrointestinal stromal tumors: a systematic review and meta-analysis

Stratified analysis

No. of studies

No. of patients

Pooled HR (95% CI)

Heterogeneity

Meta-regression

Fixed

Random

I2

p-value

Residual I2

p-value

Overall

8

553

1.283 (0.770–2.138)

1.430 (0.608–3.363)

60.8%

0.013*

  

Adjuvant imatinib treatment

      

58.96%

0.667

Yes

4

253

0.651 (0.262–1.616)

1.232 (0.185–8.204)

73.8%

0.010*

  

No

4

300

1.755 (0.947–3.254)

1.769 (0.926–3.380)

8.4%

0.351

  
  1. HR, hazard ratios; CI, confidence interval; Fixed, fixed-effects model; Random, random-effects model; *indicating heterogeneity.
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