Figure 2 | Scientific Reports

Figure 2

From: Overexpression of Suprabasin is Associated with Proliferation and Tumorigenicity of Esophageal Squamous Cell Carcinoma

Figure 2

Suprabasin expression increases in ESCC tissues and correlates with ESCC progression.

(a,b) Suprabasin expression increased in ESCC tissues (T), compared to the paired adjacent non-tumor tissue (ANT) specimens from eight patients, determined by real-time PCR analysis (a) and western blotting analysis (b). (c) Representative images of IHC analysis of ESCC specimens (clinical stage I–IV tumors) compared with normal esophageal tissue (Upper, 200×; Lower, 400×). (d) Statistical analysis of the mean optical density (MOD) of suprabasin staining in normal esophageal tissue and ESCC specimens at different clinical stages. (e) Kaplan–Meier curves of univariate analysis (log-rank) of overall survival for all patients with low versus high suprabasin expression. Bars represent the mean ± SD of three independent experiments. *P < 0.05.

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