Figure 4
Upregulation of suprabasin enhances the tumorigenicity of ESCC cells in vitro and in vivo.
(a) Representative micrographs (left) and quantification (right) of colonies formed by the indicated cells, determined by anchorage-independent growth ability assays. (b) Representative images of the tumors from all mice in each group. (c) Tumor volumes were measured on the indicated days. (d) Mean tumor weights of all mice in each group. All experiments were performed with KYSE510 and KYSE180 cells stably overexpressing or silencing suprabasin. Bars represent the mean ± SD of three independent experiments. *P < 0.05.
