Figure 1: A PPI network construction by mapping 244 DEPs to a web-based HAPPI database and its topological features. | Scientific Reports

Figure 1: A PPI network construction by mapping 244 DEPs to a web-based HAPPI database and its topological features.

From: Integrative topological analysis of mass spectrometry data reveals molecular features with clinical relevance in esophageal squamous cell carcinoma

Figure 1

(A) The seeds of 244 DEPs were mapped onto HAPPI database and were expanded to their first-degree neighbors, resulting in an extended network with 22 604 interactions between 6392 nodes. Different colors denote nodes with different degree and k-shell. (B) The degree distribution of the PPI network. (C) The contributions of the two factors in terms of factor scores versus are 52.25% and 43.71%, respectively.

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