Figure 2: Clinical performances for discrimination of ESCC and N of SDN-, DEP-, DEG- and CF-based classifiers compared with 1000 random classifiers of each data set.

(A–D) show the accuracies, sensitivities, specificities and AUCs of SDN-, DEP-, DEG- and CF-based classifiers compared with 1000 random classifiers of each data set for discrimination of ESCC and N, respectively. Note: * indicates higher values of permutated classifiers than SVM based classifiers in data set GSE 70409; SDN-, DEP-, DEG- and CF-Per indicate mean values of permutation tests.