Figure 5
Ang-(1–7)/ACE2 inhibit oxidative stress and inflammation in FFA-induced HepG2 cells.
(A) The levels of intracellular ROS were stained with DCF-DA and the fluorescence intensity of DCF-DA was measured by flow cytometry. (B) Relative protein levels of anti-oxidative stress related proteins (catalase, GPX1 and SOD2) and inflammation related proteins (TNF-α, MCP-1 and IL-8) in ACE2-overexpressing HepG2 cells. The data are presented as the mean ± SD of n = 3 independent experiments in HepG2 cells. *P < 0.05 and **P < 0.01 versus control or empty vector by one-way ANOVA.
