Table 1 Comparison between metabolites of OA incubated with rat microsomes and human microsomes (after selection both in −H and + H conditions).
Number | Rat microsomes | Human microsomes | ||||
|---|---|---|---|---|---|---|
Formula | m/z | Name | Formula | m/z | Name | |
1 | C16H14O7 | 318 | Oxidation and Internal Hydrolysis | C16H12O6 | 300 | Oxidation |
2 | C16H12O6 | 300 | Oxidation | C16H14O7 | 318 | Oxidation and Internal Hydrolysis |
3 | C16H12O7 | 316 | Di-Oxidation | C16H12O7 | 316 | Di-Oxidation |
4 | C16H14O8 | 334 | Internal Hydrolysis and Di-Oxidation | C16H14O8 | 334 | Internal Hydrolysis and Di-Oxidation |
5 | C15H12O8 | 320 | Loss of CH2+ Internal Hydrolysis and Di-Oxidation | C15H12O8 | 320 | Loss of CH2+ Internal Hydrolysis and Di-Oxidation |
6 | C15H12O7 | 304 | Loss of CH2+ Oxidation and Internal Hydrolysis | |||
7 | C16H12O8 | 332 | Tri-Oxidation | |||
8 | C15H10O5 | 270 | Loss of CH2 | |||
