Figure 8 | Scientific Reports

Figure 8

From: PE11, a PE/PPE family protein of Mycobacterium tuberculosis is involved in cell wall remodeling and virulence

Figure 8

Cytokine profile of Balb/c mice infected with Msmeg-PE11 and Msmeg-pVV at day 7 post-infection.

Balb/c mice were infected intravenously with 5 × 107 Msmeg-PE11 and Msmeg-pVV and at day 7 post-infection, the mice were sacrificed and total RNA was isolated from liver, lung and spleen. The levels of TNF-α (a), IL-1β (b), IL-10 (c) and IL-4 (d) in different tissues were measured by reverse-transcription qPCR and expression levels were normalized to corresponding GAPDH levels. The data are representative of 3 mice in each group.

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