Figure 1

Characterization of PLM.
(A) Schematic diagram of a PLM constructed for drug delivery. PTX was encapsulated into the shell of gas-filled MBs. (B) A typical bottle of PLM after mechanical activation. (C) An optical microscope of PLM, scale bar = 10 μm. (D) The bubble size distributions of the control MBs and PLM. (E–G) The MB concentrations, bubble size and drug EE of PLM after the freshly prepared PLMs were left to stand for 0.5, 6, 18 or 32 h.