Figure 4
Overview of the experimental protocol.
(A) Experimental protocol over time (days) is shown, with each vertical line on the x-axis representing a time point at intervals of one week. The arrows represent the time point of animal treatments, corresponding to balloon injury, start therapy and evaluation, respectively. (B) Diagram shows the experimental setting, with the rabbit lying supine and the site of iliac artery restenosis received with US imaging and therapy. Partial enlarged drawing of iliac artery restenosis which was perfused with PLM and received with therapy under US imaging is shown (inset). (C) The isolated fragments of the iliac artery with restenosis and without restenosis were presented. Scale bar: 2 mm. (D) The in vivo drug local delivery efficiency was determined by examining PTX amounts in the isolated iliac arteries.
