Table 5 Correlations between fetal PFASs and maternal thyroid hormones.

From: Placental Transfer of Perfluoroalkyl Substances and Associations with Thyroid Hormones: Beijing Prenatal Exposure Study

 

Maternal FT3

Maternal FT4

Maternal T3

Maternal T4

Maternal TSH

Fetal PFASs

Not-adjusted

Adjusteda

Not-adjusted

Adjusteda

Not-adjusted

Adjusteda

Not-adjusted

Adjusteda

Not-adjuste

d Adjusteda

PFOA

−0.164**

−0.169*

−0.053**

−0.089

−0.072**

−0.069

−0.040**

−0.069

−0.073**

−0.065

PFNA

−0.260**

−0.243**

−0.095**

−0.101

−0.201**

−0.165*

−0.099**

−0.103

−0.039**

−0.045

PFDA

−0.264**

−0.264**

−0.091**

−0.126

−0.249**

−0.229**

−0.101**

−0.132

−0.124**

−0.135

PFUnA

−0.293**

−0.293**

−0.037**

−0.072

−0.246**

−0.213**

−0.028**

−0.045

−0.130**

−0.155

PFDoA

−0.268**

−0.255**

−0.090**

−0.097

−0.244**

−0.224**

−0.125**

−0.134

0.047*

0.061

PFHxS

−0.185**

−0.192*

0.045*

−0.006

−0.176**

−0.172*

−0.010

−0.034

−0.028**

−0,066

PFOS

−0.249**

−0.215**

−0.004**

−0.059

−0.248**

−0.203*

−0.071**

−0.108

−0.156*

−0.173*

6:2 FTS

−0.096

−0.122

−0.002

−0.001

−0.080

−0.076

−0.048

−0.056

0.117

0.127

NMeFOSAA

0.034*

0.060

−0.014*

−0.025

−0.046*

−0.025

−0.024

−0.023

0.001**

−0.007

  1. Spearman correlation tests were used among the concentrations of PFASs and thyroid hormones with- and without adjustment influential covariates, which were selected from multivariate models. Four women with abnormal thyroid hormones levels were excluded. Units in pg/mL for 6:2 FTS and NMeFOSAA, ng/mL for other PFASs, pmol/mL for FT3 and FT4, nmol/mL for T3 and T4, μIU/mL for TSH. aAdjusted for maternal age, maternal prepregnancy BMI, maternal monthly income, maternal previous live births and neonatal type of delivery. *P < 0.05, **P < 0.01.