Figure 1: Resveratrol induces autophagy through mTOR inhibition.
From: Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition
(A) Autophagy induction was analyzed by measuring accumulation level of LC3-II. Resveratrol (100 μM), PP242 (1.25 μM), H-89 (10 μM), or a combination of two different chemicals was administered to HEK293 cells for 4 h. *P < 0.05 n = 3. (B) LC3 puncta formation induced by resveratrol (50 μM), PP242 (1.25 μM), or a combination of these chemicals was examined in HeLa cells stably expressing GFP-LC3 for 2 h. Scale bars in fluorescent pictures represent 20 μm
