Figure 3: Expression of LILR encoding transcripts in MDM samples derived from BCG vaccinated and unvaccinated donors, cultured with various mycobacterial species, as determined using qPCR analysis. | Scientific Reports

Figure 3: Expression of LILR encoding transcripts in MDM samples derived from BCG vaccinated and unvaccinated donors, cultured with various mycobacterial species, as determined using qPCR analysis.

From: Expression of the innate immune receptor LILRB5 on monocytes is associated with mycobacteria exposure

Figure 3

The y axis denotes Ct value, which is relative to GAPDH expression. Mann-Whitney analysis demonstrated a significant difference in MDM expression of LILRA3 between untreated and M. bovis treated samples from unvaccinated donors (p = 0.047), and between BCG vaccinated and unvaccinated donors in untreated (p = 0.027), BCG treated (p = 0.047) and H37Rv treated (p = 0.047) samples. Furthermore, LILRB2 demonstrated significant differences between untreated and M. bovis treated samples from unvaccinated donors (p0.016), and between BCG vaccinated and unvaccinated donors in untreated (p = 0.025) and H37Rv treated samples (p = 0.028).

Back to article page