Table 2 Brain regions with significantly higher GC values from and to left ORBsup in MDD compared with HC.

From: Causal connectivity alterations of cortical-subcortical circuit anchored on reduced hemodynamic response brain regions in first-episode drug-naïve major depressive disorder

Region name

Coordinates

Peak t-value

Abbr.

Hem

X

Y

Z

CS

Outgoing

 Frontal

Superior frontal gyrus

SFG

L

−21

54

24

290

3.30

  

R

18

33

54

152

2.79

Middle frontal gyrus

MFG

L

−24

36

45

389

2.89

  

R

39

9

57

116

3.11

Precentral gyrus

PreCG

L

−51

9

48

62

3.06

 

ACC

R

6

39

27

63

3.44

Incoming

 Frontal

Middle frontal gyrus

MFG

L

−48

12

48

383

3.21

  

R

39

51

18

290

3.41

Inferior frontal gyrus, triangular

IFGtri

L

−57

21

30

192

3.76

  

R

57

30

0

150

2.90

Inferior frontal gyrus, orbital

ORBinf

R

51

39

−12

82

3.08

  1. Hem: Hemisphere; CS: Cluster size.