Table 4 Brain regions with significant correlations between GC values and HAMD scores in MDD patients.

From: Causal connectivity alterations of cortical-subcortical circuit anchored on reduced hemodynamic response brain regions in first-episode drug-naïve major depressive disorder

Region name

C

Coordinates

Mean r

Std r

Mean p

Abbr.

Hem

X

Y

Z

CS

GC from right ORBmid

 Anterior cingulate cortex

ACC

L

−6

42

6

59

0.557

0.037

0.018

GC from left ORBinf

 Calcarine fissure

CAL

L

−15

−66

18

87

0.619

0.066

0.009

 Fusiform gyrus

FG

L

−42

−45

−21

64

0.580

0.052

0.015

  

R

27

−39

−15

66

0.572

0.042

0.015

GC to left CAU

 Insula

INS

R

36

−15

15

59

−0.642

0.066

0.007

 Middle temporal gyrus

MTG

R

66

−36

−3

102

−0.619

0.063

0.009

 Superior temporal gyrus

STG

R

48

−27

9

88

−0.591

0.057

0.013

  1. Hem: Hemisphere; CS: Cluster size.