Figure 4: New drug discovery based on the chemico-biological association between different species. | Scientific Reports

Figure 4: New drug discovery based on the chemico-biological association between different species.

From: New strategy for drug discovery by large-scale association analysis of molecular networks of different species

Figure 4

(a) Box plot for MChS score between human and plant/microbe modules and chemical similarity between NP and drug sets. (b) Correlation analysis between MChS score and chemical similarity for module pairs with MChS score >0.5. (c) Module-module relation network (MMN) between human and other species. Module pairs with MChS score >0.6 and with significant chemical similarity (P-value < 0.01) was screened out to form this network. (d) Main categories of NPs from plant/microbe modules involved in MMN. (e) Human module-disease association analysis for human modules involved in MMN.

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