Figure 1
From: Period-independent novel circadian oscillators revealed by timed exercise and palatable meals
Wild-type mice display anticipatory activity to a daily palatable meal.
Representative double-plotted actograms of wheel-running activity of wild-type male C57BL/6J mice singly housed in 18L:6D (indicated by white and black bars) with ad libitum chow for the entire experiment. From days 14 to 27 (indicated by vertical line), peanut butter was placed in the cage for 1 h (indicated by the open square box on the left of each actogram) at either ZT4 (4 h after lights-on) or ZT10 (10 h after lights-on). Mice were then maintained in ad libitum feeding conditions for 3 days (days 28–30; no peanut butter feeding). Individual actograms from all mice are shown in Supplementary Fig. S5.
