Table 3 Assessing the associations between blood pressure genetic risk scores and traditional biomarkers as potential confounders for elevated blood pressure.

From: Assessing the Causality between Blood Pressure and Retinal Vascular Caliber through Mendelian Randomisation

Traditional confounders for elevated blood pressure

SBP GRS, per 1 score increase

DBP GRS, per 1 score increase

MAP GRS, per 1 score increase

β, SE

P

β, SE

P

β, SE

P

Total cholesterol, mmol/L

0.01, 0.02

0.62

−0.02, 0.01

0.19

0.001, 0.01

0.94

LDL, mmol/L

0.05, 0.03

0.06

−0.002, 0.01

0.90

0.006

0.50

Serum glucose, mmol/L

0.02, 0.01

0.06

0.004, 0.004

0.28

0.30

0.35

Serum creatinine, mg/dl

0.04, 0.06

0.53

0.01, 0.03

0.63

−0.15

0.72

  1. Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; GRS, genetic risk score; high-density lipoprotein; LDL, low-density lipoprotein; HbA1C, glycated haemoglobin; β, beta; SE, standard error.
Back to article page