Table 2 Regression coefficients from the two-step regression modelling process used to predict post-vaccination SP titre of cattle fitted to data from a prospective field study in Turkey (October 2012–March 2013)8.
Regression model | Parameter | Serotype O | Serotype A | Serotype Asia-1 | |||
|---|---|---|---|---|---|---|---|
Coefficient [95% CI] | P | Coefficient [95% CI] | P | Coefficient [95% CI] | P | ||
Step 1: (Logistic) Titre ≥1:32 n = 1045 | Intercept [vaccinated with single dose] | 2.1 [1.8–2.5] | <0.001 | 0.6 [0.3–0.8] | <0.001 | 2.3 [1.9–2.7] | <0.001 |
Prior vaccination [effect per dose 0-≥2] † | 0.5 [0.09–0.9] | 0.02 | 0.4 [0.1–0.7] | 0.009 | 0.2 [−0.2–0.6] | 0.4 | |
Time since last vaccination [effect per day] | −0.01 [−0.02 to −0.01] | <0.001 | −0.006 [−0.009 to −0.003] | <0.001 | −0.01 [−0.02 to −0.007] | <0.001 | |
Two-dose primary course given | 1.4 [0.8–2] | <0.001 | 1.2 [0.9–1.6] | <0.001 | 1.3 [0.7–1.8] | <0.001 | |
Step 2: (Linear) Log10(SP titre) | Intercept [vaccinated with single dose] | 2.25 [2.2–2.3] | <0.001 | 2.1 [2–2.2] | <0.001 | 2.3 [2.25–2.4] | <0.001 |
Prior vaccination [effect per dose 0-≥2] † | 0.06 [0.01–0.1] | 0.02 | 0.05 [−0.001–0.1] | 0.08 | 0.06 [0.02–0.1] | 0.007 | |
Time since last vaccination [effect per day] * | −0.001 [−0.002 to −0.0006] | <0.001 | −0.0005 [−0.001 to 0.0003] | 0.2 | −0.002 [−0.003 to −0.001] | <0.001 | |
Two-dose primary course given | 0.2 [0.14–0.26] | <0.001 | 0.11 [0.06–0.17] | <0.001 | 0.17 [0.1–0.2] | <0.001 | |
n [excludes cattle with titre <1:32] | 843 | 638 | 887 | ||||