Figure 4: Invasion of Eca109 cancer cells after MT1-MMP plasmid transfection as detected by the Transwell® assay (100×). | Scientific Reports

Figure 4: Invasion of Eca109 cancer cells after MT1-MMP plasmid transfection as detected by the Transwell® assay (100×).

From: Membrane type 1-matrix metalloproteinase induces epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: Observations from clinical and in vitro analyses

Figure 4

(Panel a) Transwell® assay of Eca109 cancer cells stably transfected with the MT1-MMP plasmid. Increased cell migration was observed in Eca109 cells with ectopic expression of MT1-MMP (P < 0.01). (Panel b) Transwell® assay of Eca109 cancer cells transfected with the empty vector (mock); (Panel c) Quantitative data showing accelerated invasion of ESCC cells with MTP1-MMP overexpression. Number of cells traversing the filters from triplicate determinations was counted; bars, standard error of the mean (SEM). *P < 0.01.

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