Table 3 Risk factors of permanent hemodialysis access recreation by multivariate Cox proportional hazards model by different types of permanent hemodialysis access.

From: Statins Improve Long Term Patency of Arteriovenous Fistula for Hemodialysis

 

Overall

AVF

AVG

HR

95% CI

HR

95% CI

HR

95% CI

Statin

0.79

(0.74–0.84)**

0.74

(0.69–0.80)**

0.94

(0.83–1.07)

Age (ref = 20–39)

 40–49

1.03

(0.90–1.17)

0.99

(0.85–1.14)

1.20

(0.83–1.74)

 50–59

1.14

(1.01–1.30)*

1.09

(0.95–1.25)

1.18

(0.84–1.67)

 60–69

1.29

(1.14–1.46)**

1.20

(1.05–1.38)*

1.31

(0.93–1.85)

 ≧70

1.49

(1.31–1.70)**

1.36

(1.18–1.56)**

1.47

(1.04–2.08)*

Male

0.82

(0.78–0.86)**

0.86

(0.82–0.91)**

0.94

(0.84–1.05)

Comorbidity

 CHF

1.07

(0.98–1.15)

1.09

(0.99–1.20)

0.90

(0.78–1.06)

 CVA

1.03

(0.97–1.10)

0.99

(0.92–1.07)

0.99

(0.88–1.11)

 PVD

1.09

(1.01–1.18)*

1.13

(1.03–1.25)*

0.89

(0.76–1.04)

 DM

1.06

(0.99–1.14)

1.06

(0.98–1.15)

1.00

(0.87–1.15)

 ASHD

1.07

(1.01–1.13)*

1.06

(0.99–1.14)

1.10

(0.99–1.24)

 COPD

1.05

(0.99–1.12)

1.03

(0.95–1.11)

1.09

(0.96–1.24)

 GI disease

1.10

(1.04–1.15)**

1.11

(1.04–1.18)**

0.95

(0.86–1.05)

 Liver disease

0.99

(0.92–1.06)

0.99

(0.91–1.07)

0.90

(0.78–1.04)

 Cancer

1.12

(1.02–1.23)*

1.10

(0.98–1.23)

0.97

(0.82–1.14)

Drug

 NSAID

1.08

(1.02–1.14)*

1.04

(0.97–1.11)

1.12

(0.98–1.27)

 Aspirin

1.05

(0.99–1.11)

1.04

(0.97–1.11)

0.97

(0.87–1.08)

 Clopidogrel

0.94

(0.86–1.03)

0.90

(0.80–1.01)

1.03

(0.87–1.21)

 Warfarin

1.18

(1.03–1.37)*

1.07

(0.89–1.30)

0.99

(0.79–1.24)

 ACEI

0.96

(0.92–1.02)

0.99

(0.94–1.05)

0.91

(0.82–1.01)

 ARB

0.93

(0.88–0.98)*

0.92

(0.87–0.98)*

0.96

(0.86–1.07)

 Beta blocker

0.99

(0.94–1.05)

1.00

(0.95–1.07)

0.94

(0.84–1.04)

 Non DHP CCB

0.96

(0.90–1.02)

0.96

(0.89–1.04)

1.00

(0.88–1.14)

 DHP CCB

0.98

(0.92–1.05)

0.99

(0.92–1.07)

0.96

(0.83–1.10)

 Biguanides

1.06

(0.98–1.15)

1.06

(0.97–1.16)

1.10

(0.95–1.29)

 Sulfonylureas

1.02

(0.95–1.09)

1.03

(0.95–1.12)

1.04

(0.91–1.19)

 AGI

1.10

(1.01–1.20)*

1.13

(1.01–1.25)*

1.00

(0.84–1.18)

 TZD

0.96

(0.88–1.06)

0.91

(0.82–1.02)

1.13

(0.95–1.34)

 Meglitinides

0.97

(0.90–1.04)

0.97

(0.89–1.06)

0.96

(0.84–1.10)

 Insulin

1.09

(1.03–1.16)*

1.05

(0.98–1.13)

1.25

(1.11–1.41)**

  1. *p < 0.05; **p < 0.001
  2. Abbreviations: CHF, congestive heart failure; CVA, cerebral vascular accident; PVD, peripheral vascular disease; DM, diabetes mellitus; ASHD, atherosclerotic heart disease; COPD, chronic obstructive pulmonary disease; GI, gastrointestinal; NSAID, non steroid anti-inflammatory drug; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; DHP, dihydropyridine; CCB, calcium channel blocker; AGI, alpha glucosidase inhibitor; TZD, thiazolidinediones.
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