Table 1 Baseline data of AIS patients and healthy participants.

From: Identification of candidate diagnostic biomarkers for adolescent idiopathic scoliosis using UPLC/QTOF-MS analysis: a first report of lipid metabolism profiles

Characteristics

Discovery set

Replication set

AIS patients

Healthy controls

P

AIS patients

Healthy controls

P

Sex ratio (male: female)

4:26

0:31

0.053

3:28

11:33

0.134

Age (years ± SD)[range]

13.9 ± 1.5 (12–17)

13.5 ± 2.5 (8–16)

0.525

14 ± 2.1(11–18)

14.1 ± 2(10–16)

0.856

Weight (kilogram ± SD) [range]

50.2 ± 11(35–83)

47.5 ± 13.7(24.5–96)

0.427

46.8 ± 10.9(35–82)

50 ± 7.7(41–69)

0.257

Cobb angle of main curve a (degree ± SD)[range]

48.9 ± 13.3 (30–92)

None

48.1 ± 12.3(30–78)

None

Biochemical index

 ALT (U/L ± SD) [range]

12.5 ± 5.6(6–32)

14.8 ± ± 9.1(5–49)

0.348

11.8 ± 7.2(6–34)

16.1 ± 13.6(4–46)

0.278

 TBil (μmol/L ± SD) [range]

9.7 ± 4.2(3.8–19)

10.1 ± 5.8(3–26)

0.821

9.6 ± 4.7(4.9–23.8)

9.7 ± 4.8(4.1–20.3)

0.927

 DBil (μmol/L ± SD) [range]

3.6 ± 1.7(1.4–7.8)

3.4 ± 1.9(1.4–8.4)

0.696

3.5 ± 1.5(1.6–9.2)

4 ± 2.1(2.2–8.4)

0.441

 Cr (μmol/L ± SD) [range]

53 ± 7.7(39–69)

52.5 ± 13.6(32–85)

0.893

54.6 ± 10(36-75)

60.9 ± 14.4(40–94)

0.129

 Urea(mmol/L ± SD) [range]

4.6 ± 0.9(3–6.3)

4.9 ± 2.2(2.2–12.2)

0.629

4.4 ± 1.1(2.9–7.5)

4.1 ± 0.9(2.9–5.9)

0.335

  1. AIS, adolescent idiopathic scoliosis; SD, standard deviation; ALT, alamine aminotransferase; TBil, total bilirubin; DBil, direct bilirubin; Cr, creatinine.
  2. aCobb angle of main curve was a primary parameter to identify the severity of scoliosis.