Table 1 Baseline data of AIS patients and healthy participants.
Characteristics | Discovery set | Replication set | ||||
---|---|---|---|---|---|---|
AIS patients | Healthy controls | P | AIS patients | Healthy controls | P | |
Sex ratio (male: female) | 4:26 | 0:31 | 0.053 | 3:28 | 11:33 | 0.134 |
Age (years ± SD)[range] | 13.9 ± 1.5 (12–17) | 13.5 ± 2.5 (8–16) | 0.525 | 14 ± 2.1(11–18) | 14.1 ± 2(10–16) | 0.856 |
Weight (kilogram ± SD) [range] | 50.2 ± 11(35–83) | 47.5 ± 13.7(24.5–96) | 0.427 | 46.8 ± 10.9(35–82) | 50 ± 7.7(41–69) | 0.257 |
Cobb angle of main curve a (degree ± SD)[range] | 48.9 ± 13.3 (30–92) | None | – | 48.1 ± 12.3(30–78) | None | – |
Biochemical index | ||||||
ALT (U/L ± SD) [range] | 12.5 ± 5.6(6–32) | 14.8 ± ± 9.1(5–49) | 0.348 | 11.8 ± 7.2(6–34) | 16.1 ± 13.6(4–46) | 0.278 |
TBil (μmol/L ± SD) [range] | 9.7 ± 4.2(3.8–19) | 10.1 ± 5.8(3–26) | 0.821 | 9.6 ± 4.7(4.9–23.8) | 9.7 ± 4.8(4.1–20.3) | 0.927 |
DBil (μmol/L ± SD) [range] | 3.6 ± 1.7(1.4–7.8) | 3.4 ± 1.9(1.4–8.4) | 0.696 | 3.5 ± 1.5(1.6–9.2) | 4 ± 2.1(2.2–8.4) | 0.441 |
Cr (μmol/L ± SD) [range] | 53 ± 7.7(39–69) | 52.5 ± 13.6(32–85) | 0.893 | 54.6 ± 10(36-75) | 60.9 ± 14.4(40–94) | 0.129 |
Urea(mmol/L ± SD) [range] | 4.6 ± 0.9(3–6.3) | 4.9 ± 2.2(2.2–12.2) | 0.629 | 4.4 ± 1.1(2.9–7.5) | 4.1 ± 0.9(2.9–5.9) | 0.335 |