Table 2 Serum differential metabolites detected by UPLC/QTOF-MS of AIS patients.
No. | metabolite | RT (min) | m/z | Main fragment | formula | Tendency in AIS | VIP | Pathway |
|---|---|---|---|---|---|---|---|---|
S1 | PC(40:4) | 0.52 | 838.188 | 446.8888 | C48H88NO8P | ↓ | 1.98 | Glycerophospholipid metabolism |
378.9026 | ||||||||
258.899 | ||||||||
226.9522 | ||||||||
S2 | 2-Hexenoylcarnitine | 0.56 | 256.8824 | 191.040 | C13H23NO4 | ↑ | 17.4 | Camitine synthesis |
162.113 | ||||||||
118.0865 | ||||||||
S3 | Beta-D-Glucopyranuronic acid | 0.80 | 315.0809 | 293.0620 | C13H14O9 | ↑ | 5.03 | Glucuronidation |
160.0907 | ||||||||
132.0655 | ||||||||
S4 | DG(38:9) | 3.26 | 635.3920 | 657.3838 | C41H62O5 | ↓ | 4.19 | Glycerolipid metabolism |
S5 | MG(20:3) | 5.54 | 381.1810 | 133.0848 | C23H40O4 | ↓ | 8.79 | Glycerolipid metabolism |
S6 | LysoPC(18:2) | 8.69 | 520.3414 | 542.3232 | C26H50NO7P | ↓ | 33.38 | Glycerophospholipid metabolism |
483.2481 | ||||||||
184.0735 | ||||||||
S7 | LysoPC(16:0) | 8.89 | 518.3222 | 496.3406 | C24H50NO7P | ↓ | 5.24 | Glycerophospholipid metabolism |
459.2487 |
