Table 1 Divergent mutation cases in the adenomatous and squamous components of lung ASC.
NO. | Genetic changes | Gender/age | Smoking status | Tumour size(cm) | Node metastasis | Stage | Pleura Invasion | LVI | Status |
|---|---|---|---|---|---|---|---|---|---|
1 | G: EGFR E19 DEL S: WT | Female/58 | Never | 4 | Yes | IIIA | Yes | Yes | Died |
2 | G: EGFR E21 L858R S: WT | Female/76 | Never | 5.3 | Yes | IIIA | Yes | No | Loss of follow up |
3 | G: EGFR E19 DEL S: WT | Male/76 | Smoker | 6 | Yes | IIIA | Yes | Yes | Alive with disease |
4 | G: EGFR E20 INS | Female/62 | Never | 4 | Yes | IIIB | Yes | Yes | Died |
|  | S: EGFR E20 INS + PIK3CA E20 G1050S |  |  |  |  |  |  |  |  |
5 | G: EGFR E21 L858R | Male/43 | Never | 3.5 | No | IB | No | Yes | Alive without disease |
|  | S: EGFR E21 L858R + PIK3CA E20 H1047L |  |  |  |  |  |  |  |  |
6 | G: EGFR E19 Del | Female/47 | Never | 7 | Yes | IV | Yes | Yes | Alive with disease |
|  | S: EGFR E19 Del + PIK3CA-E20 E1034G |  |  |  |  |  |  |  |  |
