Table 1 Detection limit of the targeted NGS method.
Mutation Type | Mutation Frequency | No. of Samples | Detected by NGS |
|---|---|---|---|
SNV EGFR T790M | 1% | 4 | 3 |
3% | 3 | 3 | |
5% | 8 | 8 | |
10% | 3 | 3 | |
SNV EGFR L858R | 1% | 4 | 3 |
3% | 3 | 3 | |
5% | 8 | 8 | |
10% | 3 | 3 | |
InDel EGFR c.2235_2249del15 | 1% | 4 | 4 |
3% | 3 | 3 | |
5% | 8 | 8 | |
10% | 3 | 3 |
