Figure 8
Schematic representation of mechanism of interaction between hexon and L4-100K.
After transcription, nascent hexon polypeptide chains recognize L4-100K and bind to one side of this dumb-bell shaped protein. Once the hexon subunits bind with each other, a stable hexagonal base develops and the L4-100K protein moves to the triangular top. The mature hexon then is transported into the nucleus by the chaperone. Some chimeric hexon subunits develop a stable hexagonal base as well as a stable triangular top, the function and the movement of the L4-100K protein become hindered.
