Table 3 Immunogenicity and protective efficacy of NDV chimeric virus in 1-day-old SPF chickens*.

From: Molecular basis for the thermostability of Newcastle disease virus

Virus Immunized

No. of birds

HI titer (log2)

Protection rate (%)

rLS-T-HN

10

6.50 ± 0.58a

10/10 (100)

rTS09-C

10

2.78 ± 0.56b

10/10 (100)

rLaSota

10

7.33 ± 0.52a

10/10 (100)

PBS

10

0.00c

0/10 (0)

  1. *All birds in each group were immunized with a dose of 105.0 EID50 in a 0.1 ml volume via IN/IO routes and challenged with 104.0 EID50 NDV strain F48E9 at 14 days post-vaccination. The HI titers were expressed as log2 mean ± SD. The different lowercase letters indicate statistically significant differences (P < 0.05) of the HI titers.