Table 4 Survival of NDV chimeric virus as liquid vaccine at 30 °C.

From: Molecular basis for the thermostability of Newcastle disease virus

Virus

Titers* after incubation for days

0

4

8

12

16

rLS-T-HN

9.26 ± 0.25

8.67 ± 1.04

8.08 ± 0.72

7.24 ± 0.25

6.31 ± 0.43§

rTS09-C

9.45 ± 0.42

9.16 ± 0.34

8.49 ± 0.43

7.90 ± 1.53

6.65 ± 0.87§

rLaSota

9.38 ± 0.33

7.32 ± 0.14

5.66 ± 0.82

2.57 ± 1.13

1.91 ± 0.78‡

  1. *50% egg infectious dose, log10 per 1 ml. The mean titers were shown from three independent tests (Mean ± SD, n = 3).
  2. §SPF chickens vaccinated by IN/IO routes with 0.1 ml of the vaccine produced HI antibodies presumed to protective level.
  3. ‡SPF chickens vaccinated by IN/IO routes with 0.1 ml of the vaccine did not induce detectable HI antibody.
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