Figure 1: Evaluation of neuronal death post CHPV infection across the various brain regions.
From: Microglial activation induces neuronal death in Chandipura virus infection
(A) Represents distribution of neuron in different brain regions. Dead cells are lightly stained or unstained indicated by arrow heads. (B) Co-expression of neuronal marker (NeuN) and cell death marker (TUNEL) represents the neurons undergoing apoptosis. (C) Representative graph shows analysis of cell counted for Nissl stain from an equivalent area from separate sections. (D) Representative graph shows percentage of neurodegeneration in different brain region. Calculated as: Percentage of dead cells = (Number of cells co-expressing NeuN and TUNEL)/Number of cells expressing NeuN) ×100. (E) Representative graph demonstrates qPCR mRNA level of viral P-Protein from different brain regions. *p < 0.05,**p < 0.01 and ***p < 0.005.
