Figure 2 | Scientific Reports

Figure 2

From: SAMHD1 transcript upregulation during SIV infection of the central nervous system does not associate with reduced viral load

Figure 2

Relationship of SAMHD1 transcription, Type I interferon response and disease severity.

There was a significant positive correlation of SAMHD1 transcript and level of MX1, an indicator of the Type I interferon response (A). Comparing Mx1 (B) and SAMHD1 (C) transcript with disease severity as assigned by pathology (none, mild, moderate, or severe), the association of Mx1 with disease appeared stronger than the association of SAMHD1 and disease. Transcript abundance was normalized to the average of beta actin and GAPDH; hence, the smaller the “dCq” value, the greater the abundance.

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