Table 1 Characteristics of Pigtail Macaques Used in Study.
Animal | D.P.I. | Sex | Age (years) | Brain Viral Load | Mane-A*10 Status | CNS Disease |
|---|---|---|---|---|---|---|
1 | 4 | M | 0.7 | 781 | NT | None |
2 | 4 | M | 0.7 | 67 | NT | None |
3 | 4 | M | 1.1 | 94 | NT | None |
4 | 4 | M | 1.0 | 125 | NT | None |
5 | 4 | M | 1.0 | 146 | NT | None |
6 | 4 | M | 0.9 | 258 | NT | None |
7 | 7 | M | 3.3 | 1788 | + | NT |
8 | 7 | M | 3.6 | 2932 | − | NT |
9 | 7 | M | 3.3 | 6573 | − | NT |
10 | 7 | M | 3.0 | 6434 | − | NT |
11 | 7 | M | 3.5 | 39725 | − | NT |
12 | 7 | M | 2.3 | 1402 | − | NT |
13 | 10 | M | 2.0 | 2604 | NT | Mild |
14 | 10 | M | 1.9 | 92130 | NT | Mild |
15 | 10 | M | 1.7 | 6314 | NT | Mild |
16 | 10 | M | 1.2 | 67957 | NT | Mild |
17 | 10 | M | 1.9 | 6088 | NT | Mild |
18 | 10 | M | 0.9 | 2072 | NT | None |
19 | 14 | M | 4.2 | 13180 | − | Mild |
20 | 14 | M | 5.0 | 12069 | − | None |
21 | 14 | M | 4.1 | 4160 | − | Mild |
22 | 14 | M | 5.0 | 13987 | − | None |
23 | 14 | M | 5.5 | 12100 | + | None |
24 | 14 | M | 4.2 | 3897 | − | Mild |
25 | 21 | M | 3.3 | 1040267 | − | Mild |
26 | 21 | M | 6.7 | 154926 | − | Mild |
27 | 22 | M | 5.0 | 136689 | + | None |
28 | 22 | M | 4.7 | 26410 | − | Mild |
29 | 23 | M | 4.8 | 45630 | − | Mild |
30 | 23 | M | 6.7 | 68870 | − | None |
31 | 41 | M | 3.2 | NT | − | Mild |
32 | 42 | M | 3.2 | NT | − | Mild |
33 | 42 | M | 4 | NT | − | Moderate |
34 | 43 | M | 3.9 | NT | − | None |
35 | 43 | M | 4.2 | NT | − | Severe |
36 | 44 | M | 1.3 | NT | − | None |
37 | 44 | M | 3.4 | NT | − | Severe |
38 | 44 | M | 5.7 | NT | + | None |
39 | 45 | M | 2.5 | NT | − | None |
40 | 55 | M | 4.5 | 15900000 | − | Severe |
41 | 55 | M | 6.6 | 1905333 | − | Severe |
42 | 55 | M | 5.3 | 121300 | − | Mild |
43 | 55 | M | 4.4 | 5725000 | − | Severe |
44 | 56 | M | 8.5 | 11880000 | − | Severe |
45 | 56 | M | 4.8 | 16607 | − | Mild |
46 | 56 | M | 4.8 | 382467 | − | Moderate |
47 | 56 | M | 6.3 | 63483 | − | Mild |
48 | 57 | M | 6.5 | 8658333 | − | Severe |
49 | 66 | M | 3.2 | 34430567 | − | Severe |
50 | 85 | M | Unknown | 3523 | + | Mild |
51 | 85 | M | 2.8 | 136927 | + | Severe |
52 | 86 | M | 3.3 | 1950 | + | Mild |
C1 | N/A | M | 3.5 | Negative | NT | None |
C2 | N/A | M | 2.9 | Negative | NT | None |
C3 | N/A | M | 3.1 | Negative | NT | None |
C4 | N/A | F | 3.4 | Negative | NT | None |
C5 | N/A | F | 3.4 | Negative | NT | None |
C6 | N/A | F | 2.7 | Negative | NT | None |