Table 2 Summary of the 16 unique isolated TM binding, penetrating and then transiting peptide sequences isolated using strategy 2 (sequential binding, internalization and then entry to ME) and their characteristics.
Peptide | Frequency | Sequence | Numbers of functional amino acids | pI | ||
|---|---|---|---|---|---|---|
Basic | Acidic | Hydrophobic | ||||
BPT-1 | 5/30 | TPMVERNYNAAD | 1 | 2 | 4 | 4.37 |
BPT-2 | 3/30 | ALWPPNLHAWVP | 1 | 0 | 5 | 6.79 |
BPT-3 | 3/30 | THPSTKVPGTPA | 2 | 0 | 4 | 8.44 |
BPT-4 | 3/30 | TFNPPPPQMPST | 0 | 0 | 6 | 5.19 |
BPT-5 | 2/30 | ILVGDESDGAKP | 1 | 3 | 4 | 4.03 |
BPT-6 | 1/30 | AHSANNFDVKGI | 2 | 1 | 2 | 6.79 |
BPT-7 | 2/30 | VQNSTLSTKMDS | 1 | 1 | 3 | 5.81 |
BPT-8 | 1/30 | MVEKYATLFQSS | 1 | 1 | 3 | 5.75 |
BPT-9 | 1/30 | SHQNYHLTPQPP | 2 | 0 | 4 | 6.66 |
BPT-10 | 1/30 | APTTQRVGWDQS | 1 | 1 | 2 | 5.88 |
BPT-11 | 2/30 | MSTPLGQYTGTK | 1 | 0 | 3 | 8.34 |
BPT-12 | 1/30 | MPLMSEPALEML | 0 | 2 | 6 | 3.79 |
BPT-13 | 1/30 | NYEFSISEQSHD | 1 | 3 | 1 | 4.13 |
BPT-14 | 1/30 | VNPSSLHSHNHS | 3 | 0 | 3 | 7.00 |
BPT-15 | 1/30 | ATNVVIMTQPRP | 1 | 0 | 6 | 9.79 |
BPT-16 | 2/30 | HYPTTQLPHHKQ | 4 | 0 | 3 | 8.61 |
