Figure 5
From: Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function
Decreased energy production in IR-Mut iPSC.
(a) ATP level expressed relative to control (n = 3). (b) Ratio of ADP/ATP for control and IR-Mut iPSC (n = 3). (c) Representative western blot and quantification of phosphorylated to total AMPK expression ratio (n = 3). (d) Representative western blot and quantification of phosphorylated to total ACC expression ratio (n = 3). *p < 0.05 for IR-Mut vs. control.
